StarNerd - Sure can! I have seen it easily with a 4" newt but two things may be hindering your detection of it.
First, the spot may be out of view as the planet rotates.
Second, the spot does some fading and color changes from time to time, making it more difficult to see.
And, there is a red spot "junior", just to the lower left of the large one (almost touching it) but much smaller.
Observing the planet when it's high in the sky and on a dark sky night will enhance your chances of seeing both spots with high power. Good luck, Mr Q