No one has yet found a proof to determine whether (2)^e is rational or irrational. The same is true for the number, (pi)^e.
I have read the book, "e The Story of a Number", that chipdatajeffB recommended. It is an excellent history of the number, e.
An excellent introduction to the study of rational and irrational numbers, including methods for proving certain numbers irrational, is the book, "Numbers: Rational and Irrational", by Ivan Niven. It is available through the Mathematical Association of America.
Best wishes,
Rick